The condition that we find ourself in doesn't really make much sense.
Life, ultimately, is awry.
The way that this condition has been described in a lot of English translations of Buddhist texts is suffering.
Not being a linguist, and not knowing any Pali or Sanskrit or anything besides my own understanding of what I've read and learned, I don't think that English word really matches up with what we have.
What we have is confusion. Everything is awry, askew, split, confusing. There is a great story about it, but telling that story wouldn't be nearly as interesting as watching a nice old animated version of that story, so here is a nice link to "Monkeys Reaching for the Moon". Tell me what you think about it if you'd like.